General Cell Lines and Cell Cultures
ATCC RSC96 SCHWANN CELL RAT RATTUS
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
ATCC Pseudomonas aeruginosa; Strain PGO2354
Pseudomonas aeruginosa strain PGO2354 was collected from a sputum sample of a cystic fibrosis patient during a Phase III clinical trial that tested the effectiveness of aerosolized Tobi (Tobramycin). This whole-genome sequenced strain is propagated aerobically in trypticase soy medium and is used for drug development research.
Biotium PAX8 (Renal Cell Marker) (PAX8/1491), CF647 conjugate, 0.1mg/mL
This antibody recognizes a protein of 62 kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.Primary antibodies are available purified, o
ATCC RAB-9; Skin Fibroblast; Rabbit (Oryctolagus cuniculus)
RAB-9 is a cell that has fibroblast morphology that was isolated from the skin of a female adult rabbit. This cell line was deposited by EM Earley.
ATCC Panc 10.05; Pancreatic Carcinoma; Human (Homo sapiens)
Panc 10.05 is an epithelial cell line that was isolated in 1992 from the pancreas of a White, male adult patient with adenocarcinoma. This cell line was deposited by EM Jaffee and can be used in cancer research.
Abcam Astemizole, histamine H1 receptor antagonist and hERG K+ channel blocker, 50MG
MW 458.6 Da, Purity >99%. Potent, selective histamine H1 receptor antagonist (IC50 = 4 nM) and potent hERG K+ channel blocker (IC50 =0.9 nM). Orally active. Antiallergic agent. Active *in vivo* and *in vitro*.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter U2OS XBP1 Nuclear Translocation Cell Line, 2 vials. (93-0857C3)
The PathHunter U2OS XBP1 Nuclear Translocation Cell Line is a stable, engineered cell line for use in studying drug candidates affecting the IRE1/XBP1 pathway. This cell line enables assessment of ligand (e.g. thapsigargin) based pathway activation via detection of resulting XBP1 nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLabel-tagged XBP1 and nuclear localized EA. Upon pathway activation, induced nuclear translocation of XBP1 leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/pathways.
STEMCELL Technologies Human Peripheral Blood CD19+CD27- Naïve B Cells, Frozen, Size: 1 x 10^6 cells
Primary human CD19+ naïve B cells were isolated from peripheral blood (PB) mononuclear cells (MNCs) using negative immunomagnetic separation techniques. PB was collected using acid-citrate-dextrose solution A (ACDA) as the anticoagulant.Cells were obtained using Institutional Review Board (IRB)-approved consent forms and protocols.Certain products are only available in select territories. Please contact your local Sales representative or Product & Scientific Support at techsupport@stemcell.com for further information.Browse our Frequently Asked Questions (FAQs) (https://www.stemcell.com/primary-cells-faq) on Primary Cells.
Eurofins Discoverx PathHunter U2OS HTR2C (VGV) β-Arrestin Cell Line, 2 vials. (93-0932C3)
The PathHunter HTR2C(VGV) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin) based activation of HTR2C(VGV) GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HTR2C(VGV) and EA-tagged β-Arrestin-2. Activation of HTR2C(VGV) stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Genscript Corporation CHO-K1/GITR Stable Cell Line
Tumor necrosis factor receptor superfamily member 18 (TNFRSF18) also known as activation-inducible TNFR family receptor (AITR) or glucocorticoid-induced TNFR-related protein (GITR) is a protein that in humans is encoded by the TNFRSF18 gene GITR is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Throat, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Eurofins Discoverx PathHunter PTHR1 Activated GPCR Internalization U2OS Cell Line, 2 vials. (93-0770C3)
The PathHunter PTHR1 Activated GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of PTHR1 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged PTHR1. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting PTHR1-arrestin complex is internalized to the early endosome, leading to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC J.CaM1.6; Acute T Cell Leukemia; Human (Homo sapiens)
J.CaM1.6 (derivative mutant of Jurkat) is a T lymphoblast cell line that was isolated from the peripheral blood of a male patient with acute T cell leukemia. This cell line was deposited by A Weiss and can be used in immune system disorder and immunology research.